Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Gaessler, J; Morocutti, D; Merkl, M; Remschmidt, B; Zemann, W; Schwaiger, M.
Surgical site infections in maxillofacial trauma surgery - Single-dose versus prolonged antibiotic prophylaxis.
J Craniomaxillofac Surg. 2023; 51(10):649-654
Doi: 10.1016/j.jcms.2023.09.005
Web of Science
PubMed
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FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Schwaiger Michael
- Co-Autor*innen der Med Uni Graz
- Merkl Markus
- Morocutti Dominic
- Remschmidt Bernhard Markus Lukas
- Zemann Wolfgang
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- Abstract:
- Open reduction with internal fixation (ORIF) for facial fractures has frequently been associated with the occurrence of surgical site infections (SSIs). Perioperative antibiotic prophylaxis is customarily recommended for ORIF. Thus, the comparison of two different antibiotic regimens (i.e., single-dose and prolonged antibiotic prophylaxis) concerning the rate and severity of SSIs in facial fracture patients undergoing ORIF was the main purpose of this study. This retrospective analysis included patients who underwent ORIF for facial fractures. They were distributed into two groups. The single-dose antibiotic prophylaxis group (SDAP) received single-dose perioperative antibiotic prophylaxis, whereas the prolonged antibiotic prophylaxis group (PAP) were administered prophylactic antibiosis over a course of 5 days. 122 patients were included in the study. Nine patients in the SDAP group and 15 patients in the PAP group were affected by SSIs; no significant difference in the incidence of SSIs was found (p = 0.218). Moreover, the severity of SSIs did not significantly differ between the two groups (p = 0.982).
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Antibiotic Prophylaxis - administration & dosage
- Surgical Wound Infection - epidemiology, prevention & control, drug therapy
- Retrospective Studies - administration & dosage
- Anti-Bacterial Agents - therapeutic use
- Maxillofacial Injuries - surgery
- Find related publications in this database (Keywords)
- Maxillofacial injuries
- Open fracture reduction
- Surgical wound infection
- Antibiotic prophylaxis
- Microbial drug resistance