Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Christensen, RE; Elston, DM; Worley, B; Dirr, MA; Anvery, N; Kang, BY; Bahrami, S; Brodell, RT; Cerroni, L; Elston, C; Ferringer, T; Hurley, MY; Garton, K; Lee, JSS; Liu, YQ; Maize, JC; McNiff, JM; Rapini, RP; Sangueza, OP; Shea, CR; Zhou, C; Alam, M.
Dermatopathologic features of cutaneous squamous cell carcinoma and actinic keratosis: Consensus criteria and proposed reporting guidelines
J AM ACAD DERMATOL. 2023; 88(6): 1317-1325.
Doi: 10.1016/j.jaad.2022.12.057
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Cerroni Lorenzo
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- Abstract:
- Background: There is considerable variation in the literature regarding the dermatopathologic diagnostic features of and reporting guidelines for actinic keratosis (AK) and cutaneous squamous cell carcinoma (cSCC).Objective: To develop consensus recommendations regarding diagnostic criteria, nomenclature, and reporting of AK and cSCC. Methods: Literature review and cross-sectional multiround Delphi process including an international group of expert dermatopathologists followed by a consensus meeting.Results: Consensus was achieved regarding the key dermatopathologic features necessary for diagnosing cSCC, AK, and associated variants; grading of degree of cellular differentiation in cSCC; utility of immunohistochemistry for diagnosis of cSCC; and pathologic features that should be reported for cSCC and AK. Limitations: Consensus was not achieved on all questions considered.