Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Großpötzl, M; Kloeckl, L; Guttmann, A; Kruger, M; Gran, J; Hoeflechner, L; Brandner, M; Gaugl, H; Ivastinovic, D; Lindner, M; Riedl, R; Wedrich, A; Lindner, E.
Protective Effect of Amblyopia on Age-Related Macular Degeneration.
Am J Ophthalmol. 2024; 259:1-6
Doi: 10.1016/j.ajo.2023.07.006
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Großpötzl Manuel
- Lindner Ewald
- Co-Autor*innen der Med Uni Graz
- Brandner Martina Christine
- Gaugl Heike
- Gran Jakob Daniel
- Guttmann Andreas
- Höflechner Lukas
- Ivastinovic Domagoj
- Kruger Michael
- Lindner Marlene
- Riedl Regina
- Wedrich Andreas
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- Abstract:
- PURPOSE: Our aim was to evaluate whether patients with age-related macular degeneration (AMD) and cooccurrent amblyopia are more likely to have diseases diagnosed on both the ipsilateral and the contralateral side in a large Austrian database. DESIGN: Retrospective cross-sectional study. METHODS: Setting: Institutional practice. PATIENT POPULATION: Medical records of all patients who visited the Department of Ophthalmology of the Medical University of Graz between December 1996 and June 2021 were searched for the co-occurrence of AMD and amblyopia. MAIN OUTCOME MEASURES: Data from patients with AMD diagnosed on 1 eye side were used for further analysis. Spectral-domain optical coherence tomography images were analyzed to confirm the lateral asymmetry of AMD. RESULTS: A total of 327,443 patients were screened for the co-occurrence of AMD and amblyopia. Of them, 8742 patients had AMD diagnosed on 1 eye side and 5051 patients had unilateral amblyopia. In total, 163 patients were found to have AMD diagnosed on 1 side and unilateral amblyopia in combination. Of these, 126 patients had AMD and amblyopia on contralateral sides and 37 had AMD and amblyopia on the ipsilateral side (P < .001). CONCLUSIONS: Less amblyopic patients had AMD diagnosed on the amblyopic eye compared with the nonamblyopic eye. In cases of lateral asymmetry, the nonamblyopic eye is more likely to have the more advanced form of AMD.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Amblyopia - diagnosis
- Visual Acuity - administration & dosage
- Retrospective Studies - administration & dosage
- Cross-Sectional Studies - administration & dosage
- Macular Degeneration - complications, diagnosis
- Tomography, Optical Coherence - administration & dosage