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Wilfinger, D; Cerroni, L; Eyerich, K; Aberer, W.
Differentiation between chronic hand eczema and psoriasis using a new molecu- lar classifier in an Austrian occupational dermatology patient population
DERMATOL BERUF UMW. 2023; 71(1): 1-8. Doi: 10.5414/DBX00437
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Leading authors Med Uni Graz: Wilfinger Daniel
Co-authors Med Uni Graz: Aberer Werner; Cerroni Lorenzo
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Abstract:: (Atopic) eczema and psoriasis are com-mon inflammatory skin diseases. In occu- pational dermatology, psoriasis manuum is an important differential diagnosis to hand eczema. In many cases, these diagnoses can be differentiated by anamnestic, clini-cal and histological clarification. However, these diseases can be very similar morpho-logically and histologically, which can make differentiation difficult in individual cases. In these cases, a newly developed molecular diagnostic tool can facilitate the diagnosis. The expression of two genes is determined in biopsy material of lesional skin, put in re-lation to each other and the probability of the presence of eczema or psoriasis is cal-culated from this. Experiences with this new diagnostic tool are described on the basis of an Austrian case series.
Find related publications in this database (Keywords): occupational dermatology; eczema; psoriasis; mo- lecular classifier; molecu- lar diagnostics