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Wilfinger, D; Cerroni, L; Eyerich, K; Aberer, W.
Differentiation between chronic hand eczema and psoriasis using a new molecu- lar classifier in an Austrian occupational dermatology patient population
DERMATOL BERUF UMW. 2023; 71(1): 1-8. Doi: 10.5414/DBX00437
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Führende Autor*innen der Med Uni Graz
Wilfinger Daniel
Co-Autor*innen der Med Uni Graz
Aberer Werner
Cerroni Lorenzo
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Abstract:
(Atopic) eczema and psoriasis are com-mon inflammatory skin diseases. In occu- pational dermatology, psoriasis manuum is an important differential diagnosis to hand eczema. In many cases, these diagnoses can be differentiated by anamnestic, clini-cal and histological clarification. However, these diseases can be very similar morpho-logically and histologically, which can make differentiation difficult in individual cases. In these cases, a newly developed molecular diagnostic tool can facilitate the diagnosis. The expression of two genes is determined in biopsy material of lesional skin, put in re-lation to each other and the probability of the presence of eczema or psoriasis is cal-culated from this. Experiences with this new diagnostic tool are described on the basis of an Austrian case series.

Find related publications in this database (Keywords)
occupational dermatology
eczema
psoriasis
mo- lecular classifier
molecu- lar diagnostics
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