Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Koestenbauer, S; Zech, NH; Juch, H; Vanderzwalmen, P; Schoonjans, L; Dohr, G.
Embryonic stem cells: similarities and differences between human and murine embryonic stem cells.
Am J Reprod Immunol. 2006; 55(3):169-180
Doi: 10.1111/j.1600-0897.2005.00354.x
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- Führende Autor*innen der Med Uni Graz
- Köstenbauer Sonja
- Co-Autor*innen der Med Uni Graz
- Dohr Gottfried
- Juch Herbert
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- Abstract:
- The derivation of murine embryonic stem (mES) cell lines was reported for the first time in 1981 (Nature, 1981; 292:154-156; Proc Natl Acad Sci U S A, 1981; 78:7634-7638), and they have since proved to be a very useful tool with which to study mammalian development, which is characterized by pluripotency and differentiation. About 20 years later, the successful generation of human embryonic stem (hES) cell lines was described (Science, 1998; 282:1145-1147). Although mES and hES are derived from mammals, they cannot be looked at as being one and the same. While basic information for hES can be derived from mES, such information does not correspond on a one-to-one basis. This review gives an overview of the characteristics of embryonic stem cells with the main focus on the similarities and differences between human and mES cells.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Biological Markers - metabolism
- Embryo, Mammalian - cytology
- Humans -
- Mice -
- Stem Cells - cytology
- Transcription Factors - physiology
- Find related publications in this database (Keywords)
- embryonic stem cells
- surface markers
- transcription factors