Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Beqo, BP; Gasparella, P; Flucher, C; Spendel, S; Quehenberger, F; Haxhija, EQ.
Indications for surgical resection of complicated infantile hemangiomas in the β-blocker's era: a single-institution experience from a retrospective cohort study.
Int J Surg. 2023; 109(4):829-840
Doi: 10.1097/JS9.0000000000000324
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Beqo Besiana
- Haxhija Emir
- Co-Autor*innen der Med Uni Graz
- Flucher Christina
- Gasparella Paolo
- Quehenberger Franz
- Spendel Stephan
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- BACKGROUND AND OBJECTIVES: This study aims to review how the introduction of propranolol as the primary treatment option for children with infantile hemangiomas (IHs) has affected the use of other treatment options at our institution and to determine the indications for surgical treatment of children with IHs in the propranolol era. PATIENTS AND METHODS: The authors conducted a single-center, noncompeting, historical/retrospective cohort study to review all cases referred to the institution for IH evaluation from 2005 to 2020. The authors analyzed the complete charts of patients who received surgery from 2011 to 2020 and evaluated the reasons for each surgical intervention. Detailed descriptive statistics are provided. Logistic regression analysis and Pearson's χ2 -test were applied. RESULTS: During the study period, 592 children received treatment. From 2011, oral propranolol ( n =268; 74%) and surgery ( n =95; 26%) were the only treatments of choice for complicated IH cases. A significant decrease in the frequency of surgical treatment was observed ( P =0.01). The authors identified four main indications for surgical treatment: (1) patients with ulceration and IH size appropriate for surgical resection (15%); (2) patients whose parents preferred surgical treatment (19%); (3) patients who presented late and underwent surgery before the age of three (29%); and (4) patients with sequelae after IH involution and excision after the third year of life (37%). CONCLUSIONS: Despite the significant decrease in the need for surgical treatment of children with IHs since the introduction of propranolol, there are still several clear indications for treating IH cases where surgery plays a crucial role.
- Find related publications in this database (using NLM MeSH Indexing)
- Child - administration & dosage
- Humans - administration & dosage
- Infant - administration & dosage
- Propranolol - therapeutic use, adverse effects
- Hemangioma - drug therapy, surgery
- Retrospective Studies - administration & dosage
- Health Facilities - administration & dosage
- Skin Neoplasms - drug therapy, surgery
- Treatment Outcome - administration & dosage
- Adrenergic beta-Antagonists - therapeutic use
- Find related publications in this database (Keywords)
- children
- complicated infantile hemangioma
- indications for surgery
- propranolol
- surgery