Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Direkt zur Navigaton springen.
Direkt zum Inhalt springen.

Navigation/Suche

Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid Stoffw Microb

Prigge, R; McKnight, JA; Wild, SH; Haynes, A; Jones, TW; Davis, EA; Rami-Merhar, B; Fritsch, M; Prchla, C; Lavens, A; Doggen, K; Chao, S; Aronson, R; Brown, R; Ibfelt, EH; Svensson, J; Young, R; Warner, JT; Robinson, H; Laatikainen, T; Rautiainen, P; Delemer, B; Souchon, PF; Diallo, AM; Holl, RW; Schmid, SM; Raile, K; Tigas, S; Bargiota, A; Zografou, I; Luk, AOY; Chan, JCN; Dinneen, SF; Buckley, CM; Kgosidialwa, O; Cherubini, V; Gesuita, R; Strele, I; Pildava, S; Veeze, H; Aanstoot, HJ; Mul, D; Jefferies, C; Cooper, JG; Løvaas, KF; Battelino, T; Dovc, K; Bratina, N; Eeg-Olofsson, K; Svensson, AM; Gudbjornsdottir, S; Globa, E; Zelinska, N.
International comparison of glycaemic control in people with type 1 diabetes: an update and extension.
Diabet Med. 2022; 39(5):e14766 Doi: 10.1111/dme.14766
Web of Science PubMed FullText FullText_MUG

Co-Autor*innen der Med Uni Graz: Fritsch Maria
Altmetrics:
Dimensions Citations:
Plum Analytics:
Scite (citation analytics):
Abstract:: AIMS: To update and extend a previous cross-sectional international comparison of glycaemic control in people with type 1 diabetes. METHODS: Data were obtained for 520,392 children and adults with type 1 diabetes from 17 population and five clinic-based data sources in countries or regions between 2016 and 2020. Median HbA_1c (IQR) and proportions of individuals with HbA_1c < 58 mmol/mol (<7.5%), 58-74 mmol/mol (7.5-8.9%) and ≥75 mmol/mol (≥9.0%) were compared between populations for individuals aged <15, 15-24 and ≥25 years. Logistic regression was used to estimate the odds ratio (OR) of HbA_1c < 58 mmol/mol (<7.5%) relative to ≥58 mmol/mol (≥7.5%), stratified and adjusted for sex, age and data source. Where possible, changes in the proportion of individuals in each HbA_1c category compared to previous estimates were calculated. RESULTS: Median HbA_1c varied from 55 to 79 mmol/mol (7.2 to 9.4%) across data sources and age groups so a pooled estimate was deemed inappropriate. OR (95% CI) for HbA_1c < 58 mmol/mol (<7.5%) were 0.91 (0.90-0.92) for women compared to men, 1.68 (1.65-1.71) for people aged <15 years and 0.81 (0.79-0.82) aged15-24 years compared to those aged ≥25 years. Differences between populations persisted after adjusting for sex, age and data source. In general, compared to our previous analysis, the proportion of people with an HbA_1c < 58 mmol/l (<7.5%) increased and proportions of people with HbA_1c ≥ 75 mmol/mol (≥9.0%) decreased. CONCLUSIONS: Glycaemic control of type 1 diabetes continues to vary substantially between age groups and data sources. While some improvement over time has been observed, glycaemic control remains sub-optimal for most people with Type 1 diabetes.
Find related publications in this database (using NLM MeSH Indexing): Adult - administration & dosage; Blood Glucose - administration & dosage; Child - administration & dosage; Cross-Sectional Studies - administration & dosage; Diabetes Mellitus, Type 1 - epidemiology; Female - administration & dosage; Glycated Hemoglobin - analysis; Glycemic Control - administration & dosage; Humans - administration & dosage; Male - administration & dosage
Find related publications in this database (Keywords): glycaemic control; HbA(1c); registers of people with diabetes; type 1 diabetes