Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Minden, K; Thiel, J.
[Primary vasculitides in childhood and adulthood].
Z Rheumatol. 2022; 81(1):36-44
Doi: 10.1007/s00393-021-01141-w
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Thiel Jens
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- Abstract:
- Primary systemic vasculitides can be observed at any age. Some vasculitides occur preferentially in childhood, such as Kawasaki syndrome or immunoglobulin A (IgA) vasculitis, whereas others, such as giant cell arteritis, occur beyond the age of 50 years. Vasculitides occurring in childhood or adolescence and adulthood may have different phenotypes, different disease courses and outcomes depending on the age of manifestation. For example, those with Takayasu arteritis beginning in adolescence have different vascular involvement, a higher degree of systemic inflammation and a more aggressive course of disease than those with adult-onset disease. In contrast, IgA vasculitis is more severe in adults than in children. The causes for the age predilections and different age-dependent disease manifestations have not yet been clarified. The therapeutic principles are similar for vasculitides occurring in children or adolescents and adults. The first international evidence-based treatment recommendations are now available for juvenile vasculitides, although the evidence for certain forms of treatment is still very limited. The treatment of adult vasculitides can be guided by numerous national and international guidelines and recommendations. Many vasculitides carry a high risk of morbidity and mortality and the timely detection and treatment are therefore necessary. In this article, similarities and differences in the clinical presentations, treatment, courses and prognosis of vasculitides in children or adolescents and adults are discussed.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent - administration & dosage
- Adult - administration & dosage
- Disease Progression - administration & dosage
- Giant Cell Arteritis - administration & dosage
- Granulomatosis with Polyangiitis - administration & dosage
- Humans - administration & dosage
- IgA Vasculitis - administration & dosage
- Middle Aged - administration & dosage
- Polyarteritis Nodosa - administration & dosage
- Prognosis - administration & dosage
- Takayasu Arteritis - diagnosis, therapy
- Find related publications in this database (Keywords)
- Takayasu arteritis
- Polyarteritis nodosa
- Immunoglobulin A vasculitis
- Granulomatosis with polyangiitis