Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Sallmon, H; Berger, F; Cho, MY; Opgen-Rhein, B.
First use and limitations of Magmaris® bioresorbable stenting in a low birth weight infant with native aortic coarctation.
Catheter Cardiovasc Interv. 2019; 93(7):1340-1343
Doi: 10.1002/ccd.28300
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Sallmon Hannes
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- Abstract:
- We, herein, report the first use of a Magmaris® magnesium-based vascular scaffold for native aortic coarctation in a 1,980 g infant with multiple malformations. Due to the low body weight, complex illness, and clinical instability, it was decided to delay surgical correction. After insufficient results had been obtained by balloon angioplasty, Magmaris® implantation was chosen to bridge the patient to surgery by stabilizing left ventricular function and to allow for sufficient growth. Due to significant early stent restenosis and complete loss of radial force, the patient required balloon reangioplasty only 21 days after Magmaris® implantation and early surgical correction. In addition, high systemic sirolimus levels were detected 48 hr after the intervention (5 ng/mL). Although the bioresorbable scaffold was successfully used as a short-term bridge-to-surgery in our case, due to significant early stent failure (loss of radial force), this approach does not seem promising for long-term bridging of infants with aortic coarctation. In addition, the consequences of sirolimus-induced systemic immunosuppression may further limit the applicability of Magmaris® scaffolds in infants with congenital heart disease.
- Find related publications in this database (using NLM MeSH Indexing)
- Absorbable Implants - administration & dosage
- Aortic Coarctation - diagnostic imaging, physiopathology, therapy
- Birth Weight - administration & dosage
- Cardiovascular Agents - administration & dosage
- Endovascular Procedures - instrumentation
- Female - administration & dosage
- Humans - administration & dosage
- Infant, Low Birth Weight - administration & dosage
- Infant, Newborn - administration & dosage
- Magnesium - administration & dosage
- Prosthesis Design - administration & dosage
- Prosthesis Failure - administration & dosage
- Recurrence - administration & dosage
- Retreatment - administration & dosage
- Sirolimus - administration & dosage
- Stents - administration & dosage
- Treatment Outcome - administration & dosage
- Find related publications in this database (Keywords)
- catheter
- critical coarctation
- magnesium-based scaffold
- radial force
- stent