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SHR Neuro Cancer Cardio Lipid Metab Microb
Barikbin, P; Sallmon, H; Hüseman, D; Sarioglu, N; Weichert, A; von, Weizsäcker, K; Bührer, C; Koehne, P.
Clinical, Laboratory, and Placental Findings in Perinatal Listeriosis.
Fetal Pediatr Pathol. 2016; 35(5):307-314
Doi: 10.1080/15513815.2016.1179822
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Sallmon Hannes
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- Abstract:
- Clinical, laboratory, and placental manifestations of perinatal listeriosis are highly variable. Herein, we retrospectively analyzed all patients treated for neonatal listeriosis at the Charité University Medical Center in Berlin, Germany, 1999-2013. A total of 16 cases were identified. In 14 patients listeriosis was confirmed in neonatal specimens, while in two only the placenta tested positive. Elevated C-reactive protein and/or interleukin-6 levels were only inconsistently found, while a marked white blood cell left shift was present in all infants, if available. All but one infant manifested symptoms on the first day of life. Most patients required respiratory support, while none developed meningoencephalitis as evidenced by clinical or cerebrospinal fluid findings. Two patients died, all other patients survived without sequelae. In conclusion, perinatal listeriosis is still associated with significant morbidity and mortality. Clinical and laboratory findings are highly heterogeneous, but extreme leukocyte left shift seems to be a common feature.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult - administration & dosage
- Female - administration & dosage
- Humans - administration & dosage
- Infant, Newborn - administration & dosage
- Infant, Newborn, Diseases - pathology
- Listeriosis - congenital, pathology
- Placenta - pathology
- Pregnancy - administration & dosage
- Pregnancy Complications, Infectious - pathology
- Retrospective Studies - administration & dosage
- Young Adult - administration & dosage
- Find related publications in this database (Keywords)
- Listeriosis
- newborn
- placenta
- neonatal sepsis
- I:T ratio