Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Zechner, R; Zimmermann, R; Eichmann, TO; Kohlwein, SD; Haemmerle, G; Lass, A; Madeo, F.
FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling.
Cell Metab. 2012; 15(3): 279-91.
Doi: 10.1016/j.cmet.2011.12.018
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- Co-Autor*innen der Med Uni Graz
- Eichmann Thomas
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- Abstract:
- Lipolysis is defined as the catabolism of triacylglycerols stored in cellular lipid droplets. Recent discoveries of essential lipolytic enzymes and characterization of numerous regulatory proteins and mechanisms have fundamentally changed our perception of lipolysis and its impact on cellular metabolism. New findings that lipolytic products and intermediates participate in cellular signaling processes and that "lipolytic signaling" is particularly important in many nonadipose tissues unveil a previously underappreciated aspect of lipolysis, which may be relevant for human disease.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals - administration & dosage
- Humans - administration & dosage
- Lipase - genetics, metabolism
- Lipid Metabolism - genetics, physiology
- Lipolysis - genetics, physiology
- Signal Transduction - genetics, physiology