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SHR Neuro Cancer Cardio Lipid Metab Microb

Villa, M; O'Sullivan, D; Pearce, EL.
Glucose makes T-reg lose their temper
CANCER CELL. 2021; 39(4): 460-462. Doi: 10.1016/j.ccell.2021.03.001
Web of Science PubMed FullText FullText_MUG

Leading authors Med Uni Graz: Villa Matteo
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Abstract:: Competition for glucose regulates the balance between cancer and immune responses. New findings published in Nature show that regulatory T cells (T-reg) shape their metabolism to avoid glucose competition, thus maintaining their stability and sustaining tumor progression. This research suggests hijacking the "eating habits'' of T-reg could improve cancer therapy.