Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Villa, M; O'Sullivan, D; Pearce, EL.
Glucose makes T-reg lose their temper
CANCER CELL. 2021; 39(4): 460-462.
Doi: 10.1016/j.ccell.2021.03.001
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Villa Matteo
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- Abstract:
- Competition for glucose regulates the balance between cancer and immune responses. New findings published in Nature show that regulatory T cells (T-reg) shape their metabolism to avoid glucose competition, thus maintaining their stability and sustaining tumor progression. This research suggests hijacking the "eating habits'' of T-reg could improve cancer therapy.