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Villa, M; Qiu, J; Pearce, EL.
A Sweet Deal for Diabetes
TRENDS ENDOCRIN MET. 2018; 29(1): 1-2.
Doi: 10.1016/j.tem.2017.10.006
Web of Science
PubMed
FullText
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- Leading authors Med Uni Graz
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Villa Matteo
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- Abstract:
- Sugars have pathogenic roles in diabetes. In Nature Medicine, Zhang et al. revisit this dogma and show that mannose induces the generation of regulatory T (Treg) cells. The immunoregulatory effect of mannose not only prevented the onset of autoimmune diabetes but also blocked disease progression in new-onset diabetic mice.