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SHR Neuro Cancer Cardio Lipid Metab Microb

Villa, M; Stanczak, MA; Pearce, EL.
How to make a better T cell: in vivo CRISPR screens have some answers
CELL. 2021; 184(5): 1135-1136. Doi: 10.1016/j.cell.2021.02.003
Web of Science PubMed FullText FullText_MUG

Leading authors Med Uni Graz: Villa Matteo
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Abstract:: Understanding what regulates CD8(+) T cell responses is key to effectively harnessing these cells in human disease. In this issue of Cell, Huang et al. and Chen et al. use in vivo CRISPR screens to discover novel regulators of CD8(+) T cell immunity to engineer a more efficacious response against cancer and infections.