Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Gorantla, VS; Schneeberger, S; Brandacher, G; Sucher, R; Zhang, D; Lee, WP; Zheng, XX.
T regulatory cells and transplantation tolerance.
Transplant Rev (Orlando). 2010; 24(3):147-59
Doi: 10.1016/j.trre.2010.04.002
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- Co-Autor*innen der Med Uni Graz
- Sucher Robert
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- Abstract:
- Despite the development of successful immunosuppression protocols and tremendous improvement in short-term graft survival rates, the problem of chronic graft loss remains the bane of clinical transplantation. The induction and maintenance of transplantation tolerance is the "Holy Grail" of transplantation. The recent identification and characterization of regulatory T cells has opened up exciting opportunities for tolerance induction, immunotherapy, and immunomodulation in transplantation. This review focuses on current understanding of regulatory T cells and their role in transplantation tolerance.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals - administration & dosage
- Humans - administration & dosage
- Immunosuppressive Agents - pharmacology
- T-Lymphocytes, Regulatory - immunology
- Transplantation Immunology - administration & dosage
- Transplantation Tolerance - administration & dosage
- Transplantation, Homologous - immunology