Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Hinghofer-Szalkay, HG; Sauseng-Fellegger, G; Greenleaf, JE.
Plasma volume with alternative tilting: effect of fluid ingestion.
J Appl Physiol. 1995; 78(4):1369-1373
Doi: 10.1152/jappl.1995.78.4.1369
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- Führende Autor*innen der Med Uni Graz
- Hinghofer-Szalkay Helmut
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- Abstract:
- The present study determines the effect of repeated 70 degrees head-up tilt (HUT) on plasma volume (PV) shifts by measuring blood density (BD), plasma density (PD), and hematocrit (Hct). Eight men (18-26 yr) underwent a predrink period with two supine (P1 and P3) and two HUT (P2 and P4) phases of 45 min each. At the end of P4 they drank 10 ml/kg body wt of isotonic (290 mosmol/kg) sodium chloride (Iso) or hypotonic (< 10 mosmol/kg) unsweetened tea (Hypo) or nothing [control (Con)]. The following periods continued the supine (P5, P7)/upright (P6) sequence. BD and PD were measured from ear lobe blood; they were different (P < 0.05) between Con, Hypo, and Iso P6 and P7. The density of fluid that moved between intra- and extravascular compartments was 1,008.2 +/- 0.4 g/l and did not differ with test situations. In Con (P3, P5, P7), supine PV steadily decreased compared with P1 (P < 0.05). PV in P1, P2, and P3 of all treatments averaged 120 +/- 1, 101 +/- 1, and 115 +/- 1%, respectively, of PV in P4. Tilt-induced PV shifts ranged from -9.7 to -16.7% compared with PV during the respective previous phases. After drinking, PV increased (P < 0.05) above Con values at the end of P7 by 12.9% with Iso and by 6.6% with Hypo. Progressive hemoconcentration occurred in the nondrink supine periods; isotonic saline ingestion increased supine PV to Con level but did not stop or reverse the decrease of upright hemoconcentration.(ABSTRACT TRUNCATED AT 250 WORDS)
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Data Interpretation, Statistical -
- Drinking -
- Extracellular Space - physiology
- Fluid Shifts - physiology
- Hematocrit - physiology
- Humans - physiology
- Male - physiology
- Microcirculation - physiology
- Plasma Volume - physiology
- Posture - physiology
- Find related publications in this database (Keywords)
- Microcirculation
- Posture
- Gravitation
- Isotonic
- Fluid Shifts
- Interstitial Tissue