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Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid Stoffw Microb

Riedl, D; Licht, T; Nickels, A; Rothmund, M; Rumpold, G; Holzner, B; Grote, V; Fischer, MJ; Fischmeister, G.
Large Improvements in Health-Related Quality of Life and Physical Fitness during Multidisciplinary Inpatient Rehabilitation for Pediatric Cancer Survivors.
Cancers (Basel). 2022; 14(19): Doi: 10.3390/cancers14194855 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Co-Autor*innen der Med Uni Graz

Grote Vincent Thomas

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Abstract:

Rehabilitation is a key element in improving health-related quality of life (HRQOL) for pediatric cancer survivors. The aim of this study was to present data from a multidisciplinary inpatient rehabilitation treatment. Children took part in a four-week multidisciplinary family-oriented inpatient rehabilitation. A total of 236 children (>5-21 years) and 478 parents routinely completed electronic patient-reported outcomes (ePROs), performance-based assessments, and clinician-rated assessments before (T1) and at the end (T2) of rehabilitation. HRQOL was assessed with the PedsQL generic core and PedsQL cancer module. Data were analyzed using repeated measures analysis of variance (ANOVA). Statistically significant improvements with medium to large effect sizes were observed for most HRQOL scales (η² = 0.09-0.31), as well as performance-based and clinician-rated assessments for physical activity and functional status (η² > 0.28). Agreement between children's PROs and parents' proxy ratings was lower before (r_ICC = 0.72) than after (r_ICC = 0.86) rehabilitation. While the concordance between children and parents' assessment of changes during rehab was low to moderate (r = 0.19-0.59), the use of the performance score led to substantially increased scores (r = 0.29-0.68). The results of this naturalistic observational study thus highlight the benefits of multidisciplinary pediatric inpatient rehabilitation for childhood cancer survivors. The use of the performance score is recommended in this field.

Find related publications in this database (Keywords)

pediatric cancer

HRQOL

pediatric rehabilitation

observational study

performance score

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