Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
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Zelić, Kerep, A; Olivieri, A; Schoemans, H; Lawitschka, A; Halter, J; Pulanic, D; Dickinson, A; Greinix, HT; Pavletic, SZ; Schultz, KR; Lee, SJ; Wolff, D.
Chronic gvhd dictionary-eurograft cost action initiative consensus report.
Bone Marrow Transplant. 2023; 58(1):68-71
Doi: 10.1038/s41409-022-01837-w
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- Co-Autor*innen der Med Uni Graz
- Greinix Hildegard
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- Abstract:
- Chronic graft versus host disease (cGVHD) affects patients after allogeneic hematopoietic stem cell transplantation (alloHSCT). This orphan disease poses a challenge for clinicians and researchers. The purpose of the cGVHD Dictionary is to provide a standardized structure for cGVHD databases on an international level, reconciling differences in data retrieval and facilitate database merging. It is derived from several consensus meetings of the EUROGRAFT consortium (European Cooperation in Science and Technology-COST Action CA17138) followed by a consensus process involving European Society for Blood and Marrow Transplantation (EBMT), US GvHD consortium and Center for International Bone Marrow Transplant Registry (CIBMTR). Databases used for the dictionary were: the National Institutes of Health (NIH) database, the Center for International Blood and Marrow Transplant Research, Applying Biomarkers to Minimize Long Term Effects of Childhood/Adolescent Cancer Treatment - Pediatric Blood and Marrow Transplant Consortium database, EBMT registry, the German-Austrian-Swiss GvHD registry, Italian Blood and Marrow Transplantation Society registry and Regensburg-Göttingen-Newcastle HSCT dataset. A four-part cGVHD Dictionary was formed based on the databases, consensus, and evidence in the literature. The Dictionary is divided into: (1) Patient characteristics, (2) Transplant characteristics, (3) cGVHD characteristics and (4) patient-reported quality of life, symptom burden and functional indicators.
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- Chronic Disease - administration & dosage
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- Quality of Life - administration & dosage
- Graft vs Host Disease - etiology, diagnosis
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