Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Kurz, A; Sessler, DI; Tayefeh, F; Goldberger, R.
Poikilothermia syndrome.
J Intern Med. 1998; 244(5):431-6
Doi: 10.1046/j.1365-2796.1998.00384.x
(- Case Report)
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Kurz Andrea
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- Abstract:
- Poikilothermia syndrome is a rare cause of intrinsic thermoregulatory failure. Patients with this syndrome regulate body temperature poorly, if at all. Recently, a patient was referred to us who had clinical evidence of poikilothermia syndrome, as well as long-standing multiple sclerosis. Computerized tomography and magnetic resonance scanning failed to identify a hypothalamic lesion. The patient was gradually warmed to sweating, and then cooled to vasoconstriction and shivering. The core-temperature thresholds triggering each defence were calculated, after compensating for the changes in skin temperature. The calculated sweating threshold was 38.3 degrees C (normal: 37.0 +/- 0.3 degrees C). The vasoconstriction threshold was 34.4 degrees C (normal: 36.4 +/- 0.3 degrees C). The sweating-to-vasoconstriction interthreshold range was thus approximately 4 degrees C, which is between 10 and 20 times the normal value. The shivering threshold was 31.8 degrees C (normal: 35.6 +/- 0.3 degrees C). The vasoconstriction-to-shivering range was thus approximately 2.5 degrees C which is more than twice the normal value. The pattern of thermoregulatory failure in this patient resembled that resulting from general anaesthesia.
- Find related publications in this database (using NLM MeSH Indexing)
- Body Temperature - administration & dosage
- Body Temperature Regulation - administration & dosage
- Humans - administration & dosage
- Male - administration & dosage
- Middle Aged - administration & dosage
- Multiple Sclerosis - complications, physiopathology
- Shivering - administration & dosage
- Sweating - administration & dosage
- Syndrome - administration & dosage
- Find related publications in this database (Keywords)
- core temperature
- hyperthermia
- hypothalamus
- hypothermia
- multiple sclerosis
- poikilothermia
- shivering
- skin temperature
- stroke
- sweating
- thermoregulation
- vasoconstriction