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SHR Neuro Cancer Cardio Lipid Metab Microb

Fleischmann, E; Kurz, A; Niedermayr, M; Schebesta, K; Kimberger, O; Sessler, DI; Kabon, B; Prager, G.
Tissue oxygenation in obese and non-obese patients during laparoscopy.
Obes Surg. 2005; 15(6):813-9 Doi: 10.1381/0960892054222867 [OPEN ACCESS]
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Leading authors Med Uni Graz: Kurz Andrea
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Abstract:: BACKGROUND: Wound infection risk is inversely related to subcutaneous tissue oxygenation, which is reduced in obese patients and may be reduced even more during laparoscopic procedures. METHODS: We evaluated subcutaneous tissue oxygenation (PsqO(2)) in 20 patients with a body mass index (BMI) > or=40 kg/m(2) (obese group) and 15 patients with BMI <30 kg/m(2) (non-obese group) undergoing laparoscopic surgery with standardized anaesthesia technique and fluid administration. Arterial oxygen tension was maintained near 150 mmHg. PsqO(2) was measured from a surrogate wound on the upper arm. RESULTS: A mean FIO(2) of 51% (13%) was required in obese patients to reach an arterial oxygen tension of 150 mmHg; however, a mean FIO(2) of only 40% (7%) was required to reach the same oxygen tension in non-obese patients (P=0.007). PsqO(2) was significantly less in obese patients: 41 (10) vs 57 (15) mmHg (P<0.001). CONCLUSION: Obese patients having laparoscopic surgery require a significantly greater FIO(2) to reach an arterial oxygen tension of about 150 mmHg than non-obese patients; they also have significantly lower subcutaneous oxygen tensions. Both factors probably contribute to an increased infection risk in obese patients.
Find related publications in this database (using NLM MeSH Indexing): Adult - administration & dosage; Gastroplasty - administration & dosage; Humans - administration & dosage; Laparoscopy - administration & dosage; Middle Aged - administration & dosage; Obesity, Morbid - metabolism, surgery; Oxygen - blood, metabolism; Pneumoperitoneum, Artificial - administration & dosage; Surgical Wound Infection - metabolism
Find related publications in this database (Keywords): anesthesia; tissue oxygenation; infection; surgery; wound infection; morbid obesity