Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Fleischmann, E; Kurz, A; Niedermayr, M; Schebesta, K; Kimberger, O; Sessler, DI; Kabon, B; Prager, G.
Tissue oxygenation in obese and non-obese patients during laparoscopy.
Obes Surg. 2005; 15(6):813-9
Doi: 10.1381/0960892054222867
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- Führende Autor*innen der Med Uni Graz
- Kurz Andrea
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- Abstract:
- BACKGROUND: Wound infection risk is inversely related to subcutaneous tissue oxygenation, which is reduced in obese patients and may be reduced even more during laparoscopic procedures. METHODS: We evaluated subcutaneous tissue oxygenation (PsqO(2)) in 20 patients with a body mass index (BMI) > or=40 kg/m(2) (obese group) and 15 patients with BMI <30 kg/m(2) (non-obese group) undergoing laparoscopic surgery with standardized anaesthesia technique and fluid administration. Arterial oxygen tension was maintained near 150 mmHg. PsqO(2) was measured from a surrogate wound on the upper arm. RESULTS: A mean FIO(2) of 51% (13%) was required in obese patients to reach an arterial oxygen tension of 150 mmHg; however, a mean FIO(2) of only 40% (7%) was required to reach the same oxygen tension in non-obese patients (P=0.007). PsqO(2) was significantly less in obese patients: 41 (10) vs 57 (15) mmHg (P<0.001). CONCLUSION: Obese patients having laparoscopic surgery require a significantly greater FIO(2) to reach an arterial oxygen tension of about 150 mmHg than non-obese patients; they also have significantly lower subcutaneous oxygen tensions. Both factors probably contribute to an increased infection risk in obese patients.
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- Adult - administration & dosage
- Gastroplasty - administration & dosage
- Humans - administration & dosage
- Laparoscopy - administration & dosage
- Middle Aged - administration & dosage
- Obesity, Morbid - metabolism, surgery
- Oxygen - blood, metabolism
- Pneumoperitoneum, Artificial - administration & dosage
- Surgical Wound Infection - metabolism
- Find related publications in this database (Keywords)
- anesthesia
- tissue oxygenation
- infection
- surgery
- wound infection
- morbid obesity