Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Kempf, K; Röhling, M; Banzer, W; Braumann, KM; Halle, M; Schaller, N; McCarthy, D; Predel, HG; Schenkenberger, I; Tan, S; Toplak, H; Martin, S; Berg, A; On, Behalf, Of, The, Acoorh, Study, Group.
High-Protein, Low-Glycaemic Meal Replacement Improves Physical Health-Related Quality of Life in High-Risk Persons for Metabolic Syndrome-A Subanalysis of the Randomised-Controlled ACOORH Trial.
NUTRIENTS. 2022; 14(15):
Doi: 10.3390/nu14153161
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Toplak Hermann
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- While obesity impairs health-related quality of life (HRQOL), lifestyle interventions targeting weight reduction have been effective in improving HRQOL. Therefore, we hypothesised that a meal replacement-based lifestyle intervention, which has been shown to successfully reduce weight, would also improve HRQOL more effectively than a lifestyle intervention alone. In the international, multicenter, randomised-controlled ACOORH-trial (Almased-Concept-against- Overweight-and-Obesity-and-Related-Health-Risk), overweight or obese participants with elevated risk for metabolic syndrome (n = 463) were randomised into two groups. Both groups received telemonitoring devices and nutritional advice. The intervention group additionally used a protein-rich, low-glycaemic meal replacement for 6 months. HRQOL was estimated at baseline, after 3 and 12 months, using the SF-36 questionnaire, and all datasets providing HRQOL data (n = 263) were included in this predefined subanalysis. Stronger improvements in the physical component summary (PCS) were observed in the intervention compared to the control group, peaking after 3 months (estimated treatment difference 2.7 [1.2; 4.2]; p < 0.0001), but also in the long-term. Multiple regression analysis demonstrated that insulin levels and the achieved weight loss were associated with the mental component summary (MCS) after 12 months (p < 0.05). Thus, meal replacement-based lifestyle intervention is not only effective in weight reduction but, concomitantly, in enhancing HRQOL.
- Find related publications in this database (using NLM MeSH Indexing)
- Exercise - administration & dosage
- Humans - administration & dosage
- Hypoglycemia - administration & dosage
- Life Style - administration & dosage
- Metabolic Syndrome - complications, therapy
- Obesity - complications, therapy
- Overweight - complications, therapy
- Quality of Life - administration & dosage
- Weight Loss - administration & dosage
- Find related publications in this database (Keywords)
- health-related quality of life
- protein-rich
- low-glycaemic meal replacement
- weight reduction
- multicenter study
- RCT