Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Gabriel, M; Djavid, D; Innauer, F; Ivastinovic, D; Seidel, G; Mayer-Xanthaki, C; Ansari-Shahrezaei, S; Wedrich, A; Haas, A.
CHANGES OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY PARAMETERS AFTER INTERNAL LIMITING MEMBRANE PEELING COMPARED WITH NONPEELING IN EPIRETINAL MEMBRANE SURGERY.
Retina. 2022; 42(10): 1867-1873.
Doi: 10.1097/IAE.0000000000003567
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Gabriel Maximilian
- Co-Autor*innen der Med Uni Graz
- Djavid Daniel
- Haas Anton
- Innauer Felix
- Ivastinovic Domagoj
- Mayer-Xanthaki Christoph Fidel
- Seidel Gerald
- Wedrich Andreas
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- Abstract:
- PURPOSE: To prospectively compare microvascular changes of internal limiting membrane (ILM) peeled and nonpeeled eyes in patients with idiopathic epiretinal membranes using optical coherence tomography angiography. METHODS: Forty-two patients with epiretinal membranes underwent vitrectomy with (n = 22) or without ILM peeling (n = 20). The mean superficial capillary plexus foveal avascular zone area change between preoperative and three-month postoperative readings served as the main outcome measure. Secondary outcome parameters included mean changes in superficial capillary plexus parafoveal vessel density, central foveal thickness, retinal volume, and best-corrected visual acuity. RESULTS: Mean superficial capillary plexus foveal avascular zone area change (μm 2 ) was 59 ± 74 in the ILM nonpeeling group compared with -12 ± 86 in the ILM peeling group ( P = 0.007). Similarly, mean superficial capillary plexus parafoveal vessel density change (%) was higher in the ILM nonpeeling group (ILM nonpeeling 4 ± 4, ILM peeling -2 ± 6, P = 0.003). The mean retinal volume reduction was higher in the ILM peeling group, and this difference also reached statistical significance ( P = 0.036). There were no intergroup differences in mean central foveal thickness change and mean best-corrected visual acuity change ( P = 0.409 and P = 0.440, respectively). Epiretinal membrane/ILM separation was achieved in 23 of 51 patients. CONCLUSION: The macular microvasculature demonstrated more remodeling in the ILM nonpeeling group after three months.
- Find related publications in this database (using NLM MeSH Indexing)
- Angiography - administration & dosage
- Basement Membrane - surgery
- Epiretinal Membrane - surgery
- Humans - administration & dosage
- Retrospective Studies - administration & dosage
- Tomography, Optical Coherence - methods
- Visual Acuity - administration & dosage
- Vitrectomy - methods
- Find related publications in this database (Keywords)
- epiretinal membrane
- vitrectomy
- internal limiting membrane peeling
- optical coherence tomography angiography