Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Pink, D; West, A; Andreou, D.
[Systemic Therapy Options for Locally Advanced and Metastatic Myxoid, Dedifferentiated and Pleomorphic Liposarcoma].
Zentralbl Chir. 2020; 145(2):160-167
Doi: 10.1055/a-1117-4143
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PubMed
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- Co-authors Med Uni Graz
- Andreou Dimosthenis
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- Abstract:
- Just a few years ago, all patients with metastatic soft tissue sarcoma received the same chemotherapy drugs. However, it is now recognised that the various sarcoma subtypes are different tumours with distinct genetic alterations and different biological behaviour, so that histology-specific treatment protocols have been increasingly implemented in recent years. This is also the case for the different subtypes of liposarcoma - the myxoid/round cell variant, as well as dedifferentiated and pleomorphic liposarcoma. This article will present published data and the authors' experience with the various systemic treatment options. both in first line and in subsequent lines of treatment, as well as a brief overview of experimental treatment approaches.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Liposarcoma - administration & dosage
- Sarcoma - administration & dosage
- Soft Tissue Neoplasms - administration & dosage
- Find related publications in this database (Keywords)
- liposarcoma
- chemotherapy
- sarcoma
- myxoid
- dedifferentiated
- pleomorphic