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Evans, T; Retzlaff, CO; Geissler, C; Kargl, M; Plass, M; Muller, H; Kiehl, TR; Zerbe, N; Holzinger, A.
The explainability paradox: Challenges for xAI in digital pathology
FUTURE GENER COMP SY. 2022; 133: 281-296. Doi: 10.1016/j.future.2022.03.009
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Co-Autor*innen der Med Uni Graz
Holzinger Andreas
Kargl Michaela
Müller Heimo
Plass Markus
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Abstract:
The increasing prevalence of digitised workflows in diagnostic pathology opens the door to life-saving applications of artificial intelligence (AI). Explainability is identified as a critical component for the safety, approval and acceptance of AI systems for clinical use. Despite the cross-disciplinary challenge of building explainable AI (xAI), very few application-and user-centric studies in this domain have been carried out. We conducted the first mixed-methods study of user interaction with samples of stateof-the-art AI explainability techniques for digital pathology. This study reveals challenging dilemmas faced by developers of xAI solutions for medicine and proposes empirically-backed principles for their safer and more effective design. (C) 2022 The Authors. Published by Elsevier B.V.

Find related publications in this database (Keywords)
Explainable AI
Digital pathology
Usability
Trust
Artificial intelligence
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