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Wenger-Oehn, L; Graier, T; Ambros-Rudolph, C; Müllegger, R; Bittighofer, C; Wolf, P; Hofer, A.
Pityriasis rosea in pregnancy: A case series and literature review.
J Dtsch Dermatol Ges. 2022; 20(7):953-959 Doi: 10.1111/ddg.14763 [OPEN ACCESS]
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Leading authors Med Uni Graz
Wolf Peter
Co-authors Med Uni Graz
Ambros-Rudolph Christina
Graier Thomas
Hofer Angelika
Muellegger Robert
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Abstract:
BACKGROUND AND OBJECTIVE: Pityriasis rosea (PR), a common skin disease in young adults, may adversely affects the course of pregnancy and the unborn child. PATIENTS AND METHODS: Data from forty-six pregnant women with PR seen in the dermatological university clinic between 2003 and 2018 were analyzed and compared with patient data (n = 53) from previously published studies to determine the incidence and risk factors for an unfavorable pregnancy outcome after PR infection. RESULTS: Unfavorable pregnancy outcomes (defined as miscarriage, preterm delivery before week 37 of gestation, or birth weight < 2,500 g) were significantly less frequent in our study population than in a pooled cohort obtained from previously published studies (10.9 % vs. 39.6 %; P = 0.0012). Analysis of pooled data from our study and from previous studies revealed that the week of pregnancy at onset of PR was inversely associated with an unfavorable outcome (odds ratio [OR] = 0.937; 95 % CI 0.883 to 0.993). In addition, duration of PR (OR = 1.432; 95 % CI 1.129 to 1.827), additional extracutaneous symptoms (OR = 4.112; 95 % CI 1.580 to 10.23), and widespread rash distribution (OR 5.203, 95 % CI 1.702 to 14.89) were directly associated with unfavorable outcome. CONCLUSION: In most cases, PR does not influence pregnancy or birth outcomes.
Find related publications in this database (using NLM MeSH Indexing)
Cohort Studies - administration & dosage
Female - administration & dosage
Humans - administration & dosage
Incidence - administration & dosage
Infant, Newborn - administration & dosage
Pityriasis Rosea - diagnosis, epidemiology
Pregnancy - administration & dosage
Pregnancy Complications - diagnosis, epidemiology
Risk Factors - administration & dosage
Young Adult - administration & dosage

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