Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Hocevar, A; Bruyn, GA; Terslev, L; De Agustin, JJ; MacCarter, D; Chrysidis, S; Collado, P; Dejaco, C; Fana, V; Filippou, G; Finzel, S; Gandjbakhch, F; Hanova, P; Hammenfors, D; Hernandez-Diaz, C; Iagnocco, A; Mortada, MA; Inanc, N; Naredo, E; Ohrndorf, S; Perko, N; Schmidt, WA; Tamborrini, G; Tomsic, M; Chary-Valckenaere, I; Zabotti, A; Keen, HI; Pineda, C; D'agostino, MA; Jousse-Joulin, S.
Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjogren's syndrome: an OMERACT reliability exercise
RHEUMATOLOGY. 2022;
Doi: 10.1093/rheumatology/keab876
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Dejaco Christian
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- Abstract:
- Objective The aim of this exercise from the OMERACT Ultrasound subgroup on Sjogren's syndrome was to develop and assess the reliability of a consensus-based semiquantitative colour Doppler US scoring system for pathologic salivary gland vascularization in patients with primary Sjogren's syndrome (pSS). Methods Using the Delphi method, a colour Doppler semiquantitative scoring system for vascularization of bilateral parotid and submandibular glands was developed and tested in static images and on patients (9 pSS patients and 9 sonographers). Intra-reader and inter-reader reliability of grading the salivary glands were computed by weighted Cohen and Light's kappa analysis, respectively. Results The consensus-based semiquantitative score was: grade 0, no visible vascular signals; grade 1, focal, dispersed vascular signals; grade 2, diffuse vascular signals detected in <50% of the gland; grade 3, diffuse vascular signals in >50% of the gland. In static images, the intra- and inter-reader reliability showed excellent kappa values (95% CI) of 0.90 (0.87, 0.93) and 0.80 (0.74, 0.84), respectively, for all four salivary glands together. In patients, the intra- and inter-reader reliability for all four salivary glands together was kappa = 0.84 (0.73, 0.92) and 0.70 (0.64, 0.76), respectively. Conclusion The consensus-based colour Doppler US scoring for the evaluation of salivary gland vascularization in pSS showed a good inter-reader reliability and excellent intra-reader reliability in static images and in patients. The clinical application of the developed scoring system should be tested in clinical settings.
- Find related publications in this database (Keywords)
- primary Sjogren's syndrome
- salivary gland vascularization
- colour Doppler ultrasound
- scoring system