Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Aigner, P; Schlöglhofer, T; Plunger, LC; Beitzke, D; Wielandner, A; Schima, H; Zimpfer, D; Moscato, F.
Pump position and thrombosis in ventricular assist devices: Correlation of radiographs and CT data.
Int J Artif Organs. 2021; 44(12): 956-964.
Doi: 10.1177/03913988211017552
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- Co-authors Med Uni Graz
- Beitzke Dietrich
- Zimpfer Daniel
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- Abstract:
- Malpositioning of left ventricular assist devices (LVAD) is a risk factor for thrombosis, but its identification from clinical imaging remains challenging. X-rays and CT scans were analyzed and parameters identified that correlated to pump thrombosis. Retrospective imaging data of patients (n = 115) with HeartmateII (HMII) or HVAD were analyzed in two groups (pump-thrombosis PT, n = 15 vs matched control group NT, n = 15) using routine X-rays and CT scans. In CT, directional deviations of the inflow cannula in three-chamber and two-chamber view (α and β angles) were identified. In HVAD PT frontal radiographs showed reduced pump body area and smaller minor axis (PT 41.3 ± 4.8 mm vs NT 34.9 ± 6.0 mm, p = 0.026), and in the lateral radiographs the visibility of the inflow cannula served as a predictive parameter for PT. In HMII patients, no parameters were associated with PT. The angle α differed significantly (NT -1.2 ± 7.5°, PT -22.0 ± 4.7°, p = 0.006) in HVAD patients. Further, correlations of x-ray parameters with CT angles α and β showed that radiographs can be used to identify malpositioned pumps. Well-aligned inflow cannula positions are essential. HVAD patients with a posterior rotation of the inflow cannula have a higher risk of pump thrombosis. This risk can reliably be identified from routine radiographs.
- Find related publications in this database (using NLM MeSH Indexing)
- Heart Failure - administration & dosage
- Heart Ventricles - administration & dosage
- Heart-Assist Devices - adverse effects
- Humans - administration & dosage
- Retrospective Studies - administration & dosage
- Thrombosis - diagnostic imaging, etiology
- Tomography, X-Ray Computed - administration & dosage
- Find related publications in this database (Keywords)
- LVAD pump thrombosis
- inflow cannula position
- radiographs
- CT scan