Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Zimpfer, D; Heinisch, B; Czerny, M; Hoelzenbein, T; Taghavi, S; Wolner, E; Grimm, M.
Late vascular complications after extracorporeal membrane oxygenation support.
Ann Thorac Surg. 2006; 81(3):892-5
Doi: 10.1016/j.athoracsur.2005.09.066
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Zimpfer Daniel
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- Abstract:
- BACKGROUND: Extracorporeal membrane oxygenation support through the groin vessels is an established treatment option for patients with life-threatening conditions, resistant to medical treatment. However, because of critical status and type of vascular access, late vascular complications are a potential risk. METHODS: From January 1998 through December 2004, 174 adults (mean age, 45 +/- 19 years) undergoing either cardiac surgery (n = 54, 31.4%) or lung transplantation (n = 120, 68.6%) were supported with extracorporeal membrane oxygenation. Data were prospectively collected and retrospectively analyzed. Follow-up extended up to 60 months (mean, 30 +/- 10 months). Multivariable regression analysis was used to identify predictors of late vascular complications. RESULTS: Hospital survival was 57.3%. A total of 12 hospital survivors (12.2%) experienced late vascular complications. All late vascular complications were local stenosis at the former arterial cannulation site. Treatment was done by means of femorofemoral crossover bypass (n = 3), iliofemoral bypass (n = 1), thromboendarterectomy (n = 3), and percutaneous transluminal angioplasty (n = 5). We experienced no limb loss during follow-up. Predictors for long-term vascular complications were technical problems during extracorporeal membrane oxygenation explantation (p = 0.002; odds ratio, 23.2) and history of peripheral vascular disease (p = 0.015; odds ratio, 3.1). CONCLUSIONS: Extracorporal membrane oxygenation support is associated with the development of late vascular complications at the femoral access site. In selected patients alternative cannulation sites should be considered.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult - administration & dosage
- Cardiac Surgical Procedures - adverse effects, mortality
- Extracorporeal Membrane Oxygenation - adverse effects, methods, mortality
- Female - administration & dosage
- Hospital Mortality - administration & dosage
- Humans - administration & dosage
- Lung Transplantation - adverse effects, mortality
- Male - administration & dosage
- Middle Aged - administration & dosage
- Postoperative Complications - etiology
- Retrospective Studies - administration & dosage
- Vascular Diseases - etiology, surgery, therapy