Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Gottardi, R; Zimpfer, D; Funovics, M; Schoder, M; Lammer, J; Wolner, E; Czerny, M; Grimm, M.
Mid-term results after endovascular stent-graft placement due to penetrating atherosclerotic ulcers of the thoracic aorta.
Eur J Cardiothorac Surg. 2008; 33(6):1019-24
Doi: 10.1016/j.ejcts.2007.12.054
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Zimpfer Daniel
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- Abstract:
- BACKGROUND: To determine mid-term durability of endovascular stent-graft placement in patients with penetrating atherosclerotic ulcers (PAU) involving the thoracic aorta and to identify risk factors for death as well as early and late cardiovascular events. METHODS: From 1997 to 2006, 27 patients (mean age 66 yrs) presented with PAU (rupture n=7). Mean numeric EuroScore was 11 and mean logistic EuroScore was 35. Median follow-up was 42 (10-86) months, being complete in all patients. Outcome variables included death and occurrence of early and late cardiovascular events. RESULTS: In-hospital mortality was 11%. Primary success rate was 100%. Actuarial survival rates at 1, 3 and 5 years were 93%, 78% and 70%, respectively. Hemodynamic instability (HR 2.5, 2.1-3.9; p=0.034) as well as logistic EuroScore (HR 2.8, 2.4-4.3; p=0.019) was identified as independent predictor of early and late cardiovascular events. CONCLUSIONS: Endovascular stent-graft placement in patients with PAU is an effective palliation for a life-threatening sign of a severe systemic process. Hemodynamic instability at referral and a high preoperative risk score predict adverse outcome. During mid-term follow-up, patients are mainly limited by sequelae of their underlying disease.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult - administration & dosage
- Aged - administration & dosage
- Aged, 80 and over - administration & dosage
- Aorta, Thoracic - diagnostic imaging, pathology, surgery
- Aortic Diseases - diagnostic imaging, pathology, surgery
- Atherosclerosis - diagnostic imaging, pathology, surgery
- Blood Vessel Prosthesis Implantation - adverse effects, methods
- Epidemiologic Methods - administration & dosage
- Female - administration & dosage
- Humans - administration & dosage
- Male - administration & dosage
- Middle Aged - administration & dosage
- Stents - administration & dosage
- Tomography, X-Ray Computed - administration & dosage
- Treatment Outcome - administration & dosage
- Ulcer - diagnostic imaging, pathology, surgery
- Find related publications in this database (Keywords)
- penetrating
- atherosclerotic ulcer (PAU)
- arch rerouting
- endovascular stent-graft