Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Richards, R; Jour, G; Tafe, LJ; Pinto, A; Brčić, I; Linos, K; Kerr, DA.
Primary Pulmonary Round Cell Sarcomas: Multiple Potential Pitfalls for the Pathologist.
Int J Surg Pathol. 2022; 30(8):844-852
Doi: 10.1177/10668969221091586
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- Co-authors Med Uni Graz
- Brcic Iva
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- Abstract:
- Primary sarcomas of the lung are extremely uncommon. A diverse group of round cell sarcomas has been reported to originate in this location, including Ewing sarcoma, desmoplastic small round cell tumor, rhabdomyosarcoma, and poorly differentiated synovial sarcoma. The rarity of these tumors presents a potential pitfall; without careful study, they may easily be misidentified as the significantly more common poorly differentiated carcinoma. While histomorphology is a key aspect of correctly identifying a sarcoma, ancillary testing has become increasingly important in making a definitive diagnosis, as more and more recurrent genetic alterations are discovered and new entities are defined. We present three cases of primary round cell sarcomas of the lung that proved diagnostically challenging, describe the features and ancillary testing that led to the correct diagnoses, and discuss classic and evolving entities among sarcomas with round cell morphology.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Pathologists - administration & dosage
- Biomarkers, Tumor - genetics
- Diagnosis, Differential - administration & dosage
- Sarcoma - diagnosis, genetics
- Soft Tissue Neoplasms - pathology
- Lung - pathology
- Find related publications in this database (Keywords)
- sarcoma
- soft tissue neoplasms
- lung neoplasms
- small cell sarcoma
- Ewing sarcoma