Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Theiler-Schwetz, V; Trummer, C; Pandis, M; Pilz, S.
New hydrocortisone formulations for adrenal insufficiency
AUST J CLIN ENDOCR M. 2022; 15(1): 33-35.
Doi: 10.1007/s41969-022-00156-1
Web of Science
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- Führende Autor*innen der Med Uni Graz
- Theiler-Schwetz Verena
- Co-Autor*innen der Med Uni Graz
- Pandis Marlene
- Pilz Stefan
- Trummer Christian
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- Abstract:
- In recent years, new modified-release hydrocortisone formulations have been developed to better mimic the diurnal cortisol profile in the treatment of adrenal insufficiency. Plenadren (R), a dual-release hydrocortisone for Addison's disease, cannot mimic the early morning rise in cortisol, but has been associated with an improved quality of life and certain metabolic parameters. Chronocort (Efmody (R)), a modified-release hydrocortisone taken in a toothbrush regimen in the evening before going to bed and upon awakening, can provide a near-physiological cortisol profile and can be used in the treatment of congenital adrenal hyperplasia but not yet for Addison's disease.
- Find related publications in this database (Keywords)
- Glucocorticoid replacement
- Plenadren
- Chronocort
- Modified-release
- Adrenal insufficiency