Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Garcia-Sanchez, A; Peña-Cardelles, JF; Ordonez-Fernandez, E; Montero-Alonso, M; Kewalramani, N; Salgado-Peralvo, AO; Végh, D; Gargano, A; Parra, G; Guerra-Guajardo, LI; Kozuma, W.
Povidone-Iodine as a Pre-Procedural Mouthwash to Reduce the Salivary Viral Load of SARS-CoV-2: A Systematic Review of Randomized Controlled Trials.
Int J Environ Res Public Health. 2022; 19(5):
Doi: 10.3390/ijerph19052877
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- Co-authors Med Uni Graz
- Vegh Daniel Csaba
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- Abstract:
- The use of pre-procedural rinses has been investigated to reduce the number of viral particles and bacteria in aerosols, potentially decreasing the risk of cross-infection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during medical and dental procedures. This review aims to confirm whether there is evidence in the literature describing a reduction in salivary load of SARS-CoV-2 when povidone-iodine (PVP-I) is used as a pre-intervention mouthwash. An search of the MEDLINE, Embase, SCOPUS, and the Cochrane library databases was conducted. The criteria used followed the PRISMA® Statement guidelines. Randomized controlled trials investigating the reduction of salivary load of SARS-CoV-2 using PVP-I were included. Ultimately, four articles were included that met the established criteria. According to the current evidence, PVP-I is effective against SARS-CoV-2 in saliva and could be implemented as a rinse before interventions to decrease the risk of cross-infection in healthcare settings.
- Find related publications in this database (using NLM MeSH Indexing)
- COVID-19 - prevention & control
- Humans - administration & dosage
- Mouthwashes - administration & dosage
- Povidone-Iodine - therapeutic use
- Randomized Controlled Trials as Topic - administration & dosage
- SARS-CoV-2 - administration & dosage
- Viral Load - administration & dosage
- Find related publications in this database (Keywords)
- COVID-19
- SARS-CoV-2
- mouthwashes
- mouthrinse
- aerosols
- chlorhexidine
- povidone-iodine
- cetylpiridinium chloride
- hydrogen peroxide
- colony-forming units