Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Hengster, P; Blecha, HG; Deinhardt, F; Erfle, V; Fuchs, D; Goebel, FD; Gürtler, LG; Hausen, A; Hinterhuber, H; Reibnegger, G.
HTLV-III in persons with intravenous drug abuse. Correlation of antibodies against HTLV-III with neopterin and TH/TS
DEUT MED WOCHENSCHR. 1986; 111(12): 453-457.
Doi: 10.1055/s-2008-1068473
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- Reibnegger Gilbert
- Schauenstein Konrad
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- Abstract:
- Antibodies against HTLV-III, neopterin levels in blood and urine, TH/TS ratio and hepatitis marker were determined in 34 clinically symptom-free persons known to be intravenous drug abusers. 15 persons were positive in the ELISA and Western-blot tests. There was a strong reaction to protein p24 compared with that to protein p41. In 12 of 14 persons who were antibody-positive the neopterin level in morning urine was elevated; an abnormal TH/TS ratio was present in nine of 13 persons. In future, determination of neopterin and of antibodies against certain proteins of HTLV-III may make it possible to provide a simple way of prognosticating on the course of an HTLV-III infection.
- Find related publications in this database (using NLM MeSH Indexing)
- Acquired Immunodeficiency Syndrome - immunology
- Adult - immunology
- Antibodies, Viral - immunology
- Biopterin - analogs and derivatives
- Deltaretrovirus - immunology
- Enzyme-Linked Immunosorbent Assay - immunology
- Female - immunology
- Humans - immunology
- Injections, Intravenous - adverse effects
- Male - adverse effects
- Narcotics - administration and dosage
- Neopterin - administration and dosage
- Opioid-Related Disorders - immunology
- Risk - immunology
- Syringes - immunology