Medizinische Universität Graz - Research portal
Selected Publication:
Trattnig, S; Ba-Ssalamah, A; Noebauer-Huhmann, IM; Barth, M; Wolfsberger, S; Pinker, K; Knosp, E.
MR contrast agent at high-field MRI (3 Tesla).
Top Magn Reson Imaging. 2003; 14(5):365-75
Doi: 10.1097/00002142-200310000-00003
PubMed
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- Co-authors Med Uni Graz
- Wolfsberger Stefan
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- Abstract:
- Tumor-to-brain contrast after gadolinium administration using MP-RAGE and T1-SE scans in patients with primary and secondary brain tumors was significantly higher at 3 T than at 1.5 T. The subjective assessment of cumulative triple-dose 3 Tesla images obtained the best results in the detection of brain metastases compared with other sequences followed by 1.5 T cumulative triple-dose enhanced images. In macroadenomas of the hypophysis, contrast-enhanced 3 T MRI was superior to standard MRI in the diagnosis of cavernous sinus infiltration and in visualization of cranial nerves within the cavernous sinus. Due to higher spatial resolution, contrast-enhanced MR venography at 3 T showed more details in and around tumors than at 1.5 T, additionally enhanced by stronger susceptibility weighting and higher signal-to-noise ratio at 3 T. In summary, administration of gadolinium-based contrast agent produces higher contrast between tumor and normal brain at 3 T than at 1.5 T, helps to detect more cerebral metastases at 3 T versus 1.5 T in single and cumulative triple dose, improves the evaluation of macroadenomas of the hypophysis, and makes MR venography at 3 T clinically attractive with increase in spatial resolution within the same measurement time, thus providing more detailed information.
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