Selected Publication:
Wolfsberger, S; Czech, T; Knosp, E.
[Pituitary adenomas: neurosurgical treatment].
Wien Klin Wochenschr. 2003; 115 Suppl 2:28-32
Web of Science
PubMed
- Leading authors Med Uni Graz
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Wolfsberger Stefan
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- Abstract:
- Due to their diversity, pituitary adenomas represent an interdisciplinary therapeutic challenge in regard to endocrinology, radiology and neurosurgery. Advanced radiological methods such as magnetic resonance imaging (MRI) and the possibility of three-dimensional reconstruction have profoundly improved surgical planning and intraoperative neuronavigation. With the application of modern surgical techniques like endoscope-assisted microsurgery or pure endoscopic surgery further improvements in the treatment of pituitary adenomas at difficult locations can be expected. Major prognostic factors predicting surgical outcome are extension of the adenoma and invasivity into adjacent structures. Both may be perfectly visualized by high-resolution MRI. The proliferation marker MIB-1 as a parameter of growth-rate and invasivity of pituitary adenomas provides information for postoperative management in terms of additional treatment and follow-up imaging. The current management of pituitary adenomas is discussed according to the different therapeutic options available and new developments are presented.
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Adenoma - diagnosis, pathology, surgery
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Humans - administration & dosage
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Magnetic Resonance Imaging - administration & dosage
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Paraneoplastic Endocrine Syndromes - diagnosis, pathology, surgery
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Pituitary Gland - pathology
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Pituitary Hormones - blood
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- Find related publications in this database (Keywords)
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pituitary adenoma
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transsphenoidal surgery
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encloscopy
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magnetic resonance imaging
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cavernous sinus