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Selected Publication:

Wolfsberger, S; Czech, T; Knosp, E.
[Pituitary adenomas: neurosurgical treatment].
Wien Klin Wochenschr. 2003; 115 Suppl 2:28-32
Web of Science PubMed

 

Leading authors Med Uni Graz
Wolfsberger Stefan
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Abstract:
Due to their diversity, pituitary adenomas represent an interdisciplinary therapeutic challenge in regard to endocrinology, radiology and neurosurgery. Advanced radiological methods such as magnetic resonance imaging (MRI) and the possibility of three-dimensional reconstruction have profoundly improved surgical planning and intraoperative neuronavigation. With the application of modern surgical techniques like endoscope-assisted microsurgery or pure endoscopic surgery further improvements in the treatment of pituitary adenomas at difficult locations can be expected. Major prognostic factors predicting surgical outcome are extension of the adenoma and invasivity into adjacent structures. Both may be perfectly visualized by high-resolution MRI. The proliferation marker MIB-1 as a parameter of growth-rate and invasivity of pituitary adenomas provides information for postoperative management in terms of additional treatment and follow-up imaging. The current management of pituitary adenomas is discussed according to the different therapeutic options available and new developments are presented.
Find related publications in this database (using NLM MeSH Indexing)
Adenoma - diagnosis, pathology, surgery
Humans - administration & dosage
Magnetic Resonance Imaging - administration & dosage
Paraneoplastic Endocrine Syndromes - diagnosis, pathology, surgery
Pituitary Gland - pathology
Pituitary Hormones - blood
Pituitary Neoplasms - diagnosis, pathology, surgery

Find related publications in this database (Keywords)
pituitary adenoma
transsphenoidal surgery
encloscopy
magnetic resonance imaging
cavernous sinus
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