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Brunner, TB.
Neoadjuvant therapy for potentially resectable pancreatic cancer: an emerging paradigm?
Curr Oncol Rep. 2013; 15(2):162-9 Doi: 10.1007/s11912-012-0291-3
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Führende Autor*innen der Med Uni Graz
Brunner Thomas Baptist
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Abstract:
Although neoadjuvant chemoradiotherapy has been tested for more than two decades and can be safely delivered to patients with non-metastatic pancreatic cancer, no randomised trials have been reported until now. Here we provide an overview of the first randomised trial in patients with potentially resectable cancer and of the latest developments in neoadjuvant therapy for this group of patients. It is necessary to continue to perform clinical trials in this field to accurately identify the effect on survival and quality of life in patients with potentially resectable, borderline resectable and unresectable pancreatic cancer. Aspects of imaging for restaging and clinical prognostic factors are also discussed given they will be useful instruments for future trials.
Find related publications in this database (using NLM MeSH Indexing)
Antineoplastic Agents - therapeutic use
Chemoradiotherapy, Adjuvant - methods
Humans - administration & dosage
Neoadjuvant Therapy - methods
Pancreatic Neoplasms - therapy
Randomized Controlled Trials as Topic - administration & dosage

Find related publications in this database (Keywords)
Pancreatic cancer
Neoadjuvant chemoradiotherapy
Potentially resectable
Borderline resectable
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