Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Panje, C; Andratschke, N; Brunner, TB; Niyazi, M; Guckenberger, M.
Stereotactic body radiotherapy for renal cell cancer and pancreatic cancer : Literature review and practice recommendations of the DEGRO Working Group on Stereotactic Radiotherapy.
Strahlenther Onkol. 2016; 192(12):875-885
Doi: 10.1007/s00066-016-1053-1
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PubMed
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- Co-Autor*innen der Med Uni Graz
- Brunner Thomas Baptist
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- Abstract:
- PURPOSE: This report of the Working Group on Stereotactic Radiotherapy of the German Society of Radiation Oncology (DEGRO) aims to provide a literature review and practice recommendations for stereotactic body radiotherapy (SBRT) of primary renal cell cancer and primary pancreatic cancer. METHODS: A literature search on SBRT for both renal cancer and pancreatic cancer was performed with focus on prospective trials and technical aspects for clinical implementation. RESULTS: Data on renal and pancreatic SBRT are limited, but show promising rates of local control for both treatment sites. For pancreatic cancer, fractionated SBRT should be preferred to single-dose treatment to reduce the risk of gastrointestinal toxicity. Motion-compensation strategies and image guidance are paramount for safe SBRT delivery in both tumor entities. CONCLUSION: SBRT for renal cancer and pancreatic cancer have been successfully evaluated in phase I and phase II trials. Pancreatic SBRT should be practiced carefully and only within prospective protocols due to the risk of severe gastrointestinal toxicity. SBRT for primary renal cell cancer appears a viable option for medically inoperable patients but future research needs to better define patient selection criteria and the detailed practice of SBRT.
- Find related publications in this database (using NLM MeSH Indexing)
- Carcinoma, Renal Cell - radiotherapy
- Evidence-Based Medicine - administration & dosage
- Gastrointestinal Diseases - etiology, prevention & control
- Germany - administration & dosage
- Humans - administration & dosage
- Kidney Neoplasms - radiotherapy
- Pancreatic Neoplasms - radiotherapy
- Practice Guidelines as Topic - administration & dosage
- Radiation Injuries - etiology, prevention & control
- Radiation Oncology - standards
- Radiosurgery - adverse effects, standards
- Radiotherapy Dosage - administration & dosage
- Treatment Outcome - administration & dosage
- Find related publications in this database (Keywords)
- Stereotactic body radiotherapy
- Pancreatic cancer
- Renal cell cancer
- Pancreatic SBRT
- Renal SBRT