Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Schultheiß, M; Bettinger, D; Neeff, HP; Brunner, TB; Thimme, R.
[Hepatocellular Carcinoma: therapeutic options 2015].
Dtsch Med Wochenschr. 2015; 140(14):1063-8
Doi: 10.1055/s-0041-102333
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Brunner Thomas Baptist
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- The incidence of hepatocellular carcinoma (HCC), a common neoplasm, is rising and the prognosis is poor. Many factors have to be taken into account when deciding on the best mode of therapy, like tumor size and number, liver function, sequelae of portal hypertension or other comorbidities. These factors are reflected in the Barcelona Clinic Liver Cancer (BCLC) classification. Resection, radiofrequency ablation (RFA) and liver transplantation can be seen as curative therapies for the early and localized HCC. For the intermediate state of the HCC, there are other therapeutic modalities in therapy available: transarterial chemoembolization (TACE), selective internal radiation therapy (SIRT, rarer occasions), off label: stereotactic body radiation therapy (SBRT). At the moment, Sorafenib is the only option in treating advanced stages of HCC. Alternative treatment strategies, like e.g. immunological therapies, are being investigated.
- Find related publications in this database (using NLM MeSH Indexing)
- Antineoplastic Agents - administration & dosage
- Carcinoma, Hepatocellular - diagnosis, therapy
- Chemoembolization, Therapeutic - methods
- Chemoradiotherapy - methods
- Combined Modality Therapy - methods
- Evidence-Based Medicine - administration & dosage
- Humans - administration & dosage
- Internationality - administration & dosage
- Liver Neoplasms - diagnosis, therapy
- Liver Transplantation - administration & dosage
- Niacinamide - administration & dosage, analogs & derivatives
- Phenylurea Compounds - administration & dosage
- Sorafenib - administration & dosage
- Find related publications in this database (Keywords)
- Hepatitis B
- hepatitis C
- molecular virology
- pathogenesis
- antiviral therapy