Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Klocker, EV; Balic, M; Steger, G.
Molecular profiling leading to personalized treatment in breast cancer
MEMO-MAG EUR MED ONC. 2022;
Doi: 10.1007/s12254-021-00792-4
Web of Science
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- Führende Autor*innen der Med Uni Graz
- Klocker Eva Valentina
- Co-Autor*innen der Med Uni Graz
- Balic Marija
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- Abstract:
- With the development of various targeted therapies in breast cancer, detection of biomarkers for predicting treatment efficacy gains importance. With the definition of intrinsic subtypes, breast cancer has paved the way for personalized treatment. Already known and recently recognized targets play an important role both in metastatic and early breast cancer. As a result, early molecular profiling is becoming a part of early diagnostic work-up. Notwithstanding, further treatment targets and agents are needed, particularly in the most aggressive subtype encompassing heterogenous diseases under the group of triple negative breast cancer.
- Find related publications in this database (Keywords)
- Molecular signature
- Targeted therapy
- Biomarkers
- Breast cancer
- Next generation sequencing