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Wittmann, L; Turrina, C; Schwaminger, SP.
The Effect of pH and Viscosity on Magnetophoretic Separation of Iron Oxide Nanoparticles
MAGNETOCHEMISTRY. 2021; 7(6): 80 Doi: 10.3390/magnetochemistry7060080
Web of Science FullText FullText_MUG

Leading authors Med Uni Graz: Schwaminger Sebastian
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Abstract:: Magnetic nanoparticles (MNPs) are used for magnetophoresis-based separation processes in various biomedical and engineering applications. Essential requirements are the colloidal stability of the MNPs and the ability to be separated even in low magnetic field gradients. Bare iron oxide nanoparticles (BIONs) with a diameter of 9.2 nm are synthesized via coprecipitation, exhibiting a high saturation magnetization of 70.84 Am-2 kg(-1) and no remanence. In our study, zeta potential, dynamic light scattering (DLS), and sedimentation analysis show that the aggregation behavior of BIONs is influenced by pH and viscosity. Small aggregate clusters are formed with either low or high pH values or increased viscosity. Regarding magnetophoresis-based separation, a higher viscosity leads to lower magnetophoretic velocities, similar to how small aggregates do. Additionally, cooperative magnetophoresis, the joint motion of strongly interacting particles, affects the separation of the BIONs, too. Our study emphasizes the effect of pH and viscosity on the physicochemical characteristics of MNPs, resulting in different aggregation behavior. Particularly, for high viscous working media in downstream processing and medicine, respectively, the viscosity should be taken into account, as it will affect particle migration.
Find related publications in this database (Keywords): magnetophoresis; magnetic separation process; iron oxide nanoparticles; aggregation; pH; viscosity; sedimentation analyzer; zeta potential; hydrodynamic diameter