Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Denz, H; Fuchs, D; Hausen, A; Huber, H; Nachbaur, D; Reibnegger, G; Thaler, J; Werner, ER; Wachter, H.
Value of urinary neopterin in the differential diagnosis of bacterial and viral infections.
Klin Wochenschr. 1990; 68(4):218-222
Doi: 10.1007/BF01662720
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Co-Autor*innen der Med Uni Graz
- Reibnegger Gilbert
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Neopterin is released by stimulated macrophages. In this study we analyzed the diagnostic potential of urinary neopterin concentrations in patients with bacterial and viral infection. All but one of 17 patients with viral infection had increased urinary neopterin concentrations. Patients with bacterial urinary tract infection also showed increased neopterin concentrations, whereas patients with bacterial pneumonia had significantly lower neopterin levels. In addition, patients with acute bacterial pneumonia had lower neopterin levels than patients with protracted infection. A significant inverse correlation between urinary neopterin and hemoglobin concentrations was found. Neopterin concentrations could serve as a helpful additional marker of infectious diseases. Combined with other clinical and laboratory parameters it is a useful parameter for distinguishing between viral and bacterial origins of infection, as was shown by multivariate stepwise linear discriminant analysis.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Aged, 80 and over -
- Bacterial Infections - diagnosis
- Biopterin - analogs and derivatives
- Diagnosis, Differential - analogs and derivatives
- Female - analogs and derivatives
- Gastroenteritis - diagnosis
- Hepatitis A - diagnosis
- Humans - diagnosis
- Male - diagnosis
- Middle Aged - diagnosis
- Neopterin - diagnosis
- Respiratory Tract Infections - diagnosis
- Urinary Tract Infections - diagnosis
- Virus Diseases - diagnosis