Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Fuith, LC; Fuchs, D; Hausen, A; Hetzel, H; Reibnegger, G; Werner, ER; Wachter, H.
Urinary neopterin excretion in patients with uterine sarcomas.
Cancer. 1990; 65(5):1228-1231
Doi: 10.1002/1097-0142(19900301)65:5<1228::AID-CNCR2820650532>3.0.CO;2-V
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- Co-Autor*innen der Med Uni Graz
- Reibnegger Gilbert
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- Abstract:
- Neopterin, a pyrazinopyrimidine compound, is a marker of activation of cell-mediated immunity. Urinary neopterin concentrations were measured in a total of 44 patients with uterine sarcomas. Pretherapeutic neopterin excretions were elevated in 78% (14/18). The mean neopterin concentration of patients with sarcomas was significantly higher (P less than 0.0001) than that obtained in women with benign myomas and healthy controls. Furthermore, a significant correlation of normal or raised neopterin concentrations with the clinical course of disease was found. These data suggest that urinary neopterin measurement might be a useful immunologic marker for women with uterine sarcomas.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Aged -
- Biopterin - analogs and derivatives
- Female - analogs and derivatives
- Humans - analogs and derivatives
- Middle Aged - analogs and derivatives
- Neoplasm Staging - analogs and derivatives
- Neopterin - analogs and derivatives
- Sarcoma - pathology
- Uterine Neoplasms - pathology