Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Denz, H; Fuchs, D; Huber, H; Nachbaur, D; Reibnegger, G; Thaler, J; Werner, ER; Wachter, H.
Correlation between neopterin, interferon-gamma and haemoglobin in patients with haematological disorders.
Eur J Haematol. 1990; 44(3):186-189
Doi: 10.1111/j.1600-0609.1990.tb00374.x
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- Co-Autor*innen der Med Uni Graz
- Reibnegger Gilbert
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- Abstract:
- In this study, we further investigated a possible link between activation of cell-mediated immunity and anaemia in patients with haematological neoplasias. We compared serum concentrations of interferon-gamma and neopterin with haemoglobin levels. Significantly increased interferon-gamma and neopterin concentrations indicated persistent activation of cell-mediated immunity. Neopterin levels correlated significantly to interferon-gamma concentrations and inversely to haemoglobin levels. The data indicate an association between activated macrophages and the development of anaemia in patients with haematological neoplasias.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Anemia - blood
- Biopterin - analogs and derivatives
- Female - analogs and derivatives
- Hematologic Diseases - blood
- Hemoglobins - metabolism
- Humans - metabolism
- Immunity, Cellular - metabolism
- Interferon Type II - blood
- Male - blood
- Middle Aged - blood
- Neopterin - blood