Medizinische Universität Graz - Research portal
Selected Publication:
Dotevall, L; Fuchs, D; Reibnegger, G; Wachter, H; Hagberg, L.
Cerebrospinal fluid and serum neopterin levels in patients with Lyme neuroborreliosis.
Infection. 1990; 18(4):210-214
Doi: 10.1007/BF01643387
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- Co-authors Med Uni Graz
- Reibnegger Gilbert
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- Abstract:
- Elevated (greater than 3.0 nmol/l) cerebrospinal fluid neopterin concentrations were observed in 20 of 21 patients with Lyme neuroborreliosis compared with three of 11 control patients with headache, back pain or psychoneurotic disorders. Neopterin concentrations were correlated to mononuclear cell counts and protein concentrations in the cerebrospinal fluid (CSF). Following antibiotic treatment, CSF neopterin levels decreased. Serum neopterin levels were not significantly raised in patients with neuroborreliosis when compared to control subjects. Neopterin levels as well as cell count and protein concentration in the CSF are valuable inflammation markers of disease activity in Lyme neuroborreliosis.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Aged -
- Aged, 80 and over -
- Biopterin - analogs and derivatives
- Cerebrospinal Fluid - cytology
- Cerebrospinal Fluid Proteins - analysis
- Child - analysis
- Female - analysis
- Humans - analysis
- Immunoglobulin G - analysis
- Leukocytes, Mononuclear - cytology
- Lyme Disease - blood
- Male - blood
- Middle Aged - blood
- Neopterin - blood
- Nervous System Diseases - blood