Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Schuster, V; Herold, M; Wachter, H; Reibnegger, G.
Serum concentrations of interferon gamma, interleukin-6 and neopterin in patients with infectious mononucleosis and other Epstein-Barr virus-related lymphoproliferative diseases.
Infection. 1993; 21(4):210-213
Doi: 10.1007/BF01728890
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- Co-Autor*innen der Med Uni Graz
- Reibnegger Gilbert
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- Abstract:
- Serum levels of interferon gamma, interleukin-6 and neopterin were determined in 15 patients with different forms of Epstein-Barr virus-associated diseases: acute self-limiting infectious mononucleosis, chronic active infectious mononucleosis and X-linked lymphoproliferative syndrome. In patients with acute type of infection, neopterin, interferon gamma and interleukin-6 were elevated in nearly all patients. In contrast, the situation was less clear-cut in the other EBV-associated diseases; particularly interleukin-6 was undetectable in most cases. The results suggest that concomitant measurement of these diverse immune activation markers may provide interesting insights into the interactions between the virus and the host, and may also lead to therapeutic consequences.
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- Female - analogs and derivatives
- Herpesviridae Infections - blood
- Herpesvirus 4, Human - blood
- Humans - blood
- Infant - blood
- Infectious Mononucleosis - blood
- Interferon Type II - blood
- Interleukin-6 - blood
- Lymphoproliferative Disorders - blood
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