Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Mirzaei, R; Mohammadzadeh, R; Mirzaei, H; Sholeh, M; Karampoor, S; Abdi, M; Alikhani, MY; Kazemi, S; Ahmadyousefi, Y; Jalalifar, S; Yousefimashouf, R.
Role of microRNAs in Staphylococcus aureus infection: Potential biomarkers and mechanism.
IUBMB Life. 2020; 72(9): 1856-1869.
Doi: 10.1002/iub.2325
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Mohammadzadeh Rokhsareh
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- Abstract:
- Staphylococcus aureus is known as a common pathogen that colonizes 30% of healthy humans. Additionally, this bacterium can cause a number of serious infections, that is, endocarditis, bacteremia, pneumonia, wound, skin infections, and tissue abscesses. A variety of cellular and molecular pathways and targets are involved in response against S. aureus. Among them, microRNAs (miRNAs) have crucial roles in response against S. aureus. In this regard, it has been shown that these molecules exert their regulatory roles via modulating a wide range of events, such as inflammatory reactions, host innate, and adaptive immunity. Current works have provided insight into the crucial involvement of miRNAs in immune defense toward Staphylococcal infections. Herein, we highlighted the current findings on the deregulation of different miRNAs in S. aureus-infected cells. Moreover, we summarized the mechanisms and targets of miRNAs in S. aureus infections.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals - administration & dosage
- Biomarkers - analysis
- Humans - administration & dosage
- Immunity, Innate - genetics, immunology
- MicroRNAs - genetics
- Staphylococcal Infections - diagnosis, genetics, immunology, microbiology
- Staphylococcus aureus - immunology
- Find related publications in this database (Keywords)
- immune response
- Biomarker
- infection
- microRNAs
- Staphylococcus aureus