Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Mirzaei, R; Mohammadzadeh, R; Mahdavi, F; Badrzadeh, F; Kazemi, S; Ebrahimi, M; Soltani, F; Kazemi, S; Jeda, AS; Darvishmotevalli, M; Yousefimashouf, R; Keyvani, H; Karampoor, S.
Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine.
Int Immunopharmacol. 2020; 88: 106928
Doi: 10.1016/j.intimp.2020.106928
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- Co-Autor*innen der Med Uni Graz
- Mohammadzadeh Rokhsareh
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- Abstract:
- Coronavirus disease 2019 (COVID-19) is a pandemic infectious disease caused by the novel coronavirus called SARS-CoV-2. There is a gap in our understanding regarding the immunopathogenesis of COVID-19. However, many clinical trials are underway across the world for screening effective drugs against COVID-19. Nevertheless, currently, no proven effective therapies for this virus exists. The vaccines are deemed as a significant part of disease prevention for emerging viral diseases, since, in several cases, other therapeutic choices are limited or non-existent, or that diseases result in such an accelerated clinical worsening that the efficacy of treatments is restricted. Therefore, effective vaccines against COVID-19 are urgently required to overcome the tremendous burden of mortality and morbidity correlated with SARS-CoV-2. In this review, we will describe the latest evidence regarding outstanding vaccine approaches and the challenges for vaccine production.
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- Antibodies, Viral - blood
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- COVID-19 Vaccines - administration & dosage
- Clinical Trials as Topic - administration & dosage
- Coronavirus Infections - immunology, prevention & control
- Drug Development - methods
- Humans - administration & dosage
- Immunogenicity, Vaccine - administration & dosage
- Lung - immunology, virology
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- SARS-CoV-2 - administration & dosage
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- Find related publications in this database (Keywords)
- COVID-19
- SARS-CoV-2
- Immunopathogenesis
- Vaccines